PREDICT PhD completions – Dr Elliot Long PhD and Dr Jeremy Furyk PhD

Congratulations to PREDICT sponsored PhD students Dr Elliot Long and Dr Jeremy Furyk who were recently awarded their PhDs. Elliot’s PhD work in relation to Sepsis and Jeremy’s PhD on Convulsive Status Epilepticus and Consent in ED are cutting edge and both have led to multiple publications. They also set the stage for several planned follow up projects.

We join in acknowledging this significant achievement and look forward to working with them both on future research. All the best for your future careers Elliot and Jeremy.

 

 

 

 

New PREDICT publications

Shavit I, Rimon A, Waisman Y, Borland ML, Phillips N, Kochar A, Cheek JA, Gilhotra Y, Furyk J, Neutze J, Dalziel SR, Lyttle MD, Bressan S, Donath S, Hearps S, Oakley E, Crowe L, Babl FE; Paediatric Research in Emergency Departments International Collaborative (PREDICT). Performance of Two Head Injury Decision Rules Evaluated on an External Cohort of 18,913 Children. J Surg Res. 2019 Aug 20;245:426-433. doi: 10.1016/j.jss.2019.07.090. PMID: 31442746 [Epub ahead of print] [link]

Eapen N, Davis GA, Borland ML, Phillips N, Oakley E, Hearps S, Kochar A, Dalton S, Cheek J, Furyk J, Lyttle MD, Bressan S, Crowe L, Dalziel S, Tavender E, Babl FE. Clinically important sport-related traumatic brain injuries in children. Med J Aust. 2019 Aug 16. doi: 10.5694/mja2.50311. PMID: 31420871  [Epub ahead of print].

Bressan S, Kochar A, Oakley E, Borland M, Phillips N, Dalton S, Lyttle MD, Hearps S, Cheek JA, Furyk J, Neutze J, Dalziel S, Babl FE; Paediatric Research in Emergency Department International Collaborative (PREDICT) group. Traumatic brain injury in young children with isolated scalp haematoma. Arch Dis Child. 2019 Jul;104(7):664-669. doi: 10.1136/archdischild-2018-316066. Epub 2019 Mar 4. [link].

 

PREDICT members meeting – you must register to attend

Trybooking is NOW OPEN to register for the PREDICT members meeting on 24/10/19.  The DEADLINE is now closed to request sponsorship for accommodation and/or flights and successful applicants have been notified via email. See full details below:

The PREDICT members meeting will be held in October 2019, aligned with the PAC/APLS conference and held at the same venue.

DATE: Thursday 24/10/19 (one day meeting only this year)

TIME: 10.00am – 5.30pm (later start time to accommodate morning flights from eastern states)

VENUE: Pan Pacific Perth, 207 Adelaide Terrace, Perth

REGISTRATION

  • All attendees must register via Trybooking and be a PREDICT member. Registration is now open.
  • Registrations close on Friday 18/10/19.
  • If you wish to attend and are not a PREDICT member contact Cate Wilson regarding membership application prior to proceeding with Trybooking.
  • Accommodation and travel will be booked by Marian for funded attendees and the PREDICT Executive only. Other members attending the meeting are requested to make their own arrangements.
  • Meeting agenda will be available closer to the date.

    Dinner
  • This year, the PREDICT dinner will be held the evening before the meeting on Wednesday 23/10/2019 at 7.30pm at the Sentinel Bar and Grill which is a short walk from the Pan Pacific.
  • The dinner includes a 3 course menu with a range of meat, seafood and vegetarian options. Drinks are available at bar prices.
  • Payment of $65 (plus 50 cent booking fee) must be made via Trybooking during the registration process.
  • Booking and payment must be received by Friday 18/10/19 as the restaurant requires confirmation of numbers by this deadline.

“Getting to know you”- Meet new member Kamal Singh

Our “Getting to Know You” segment ensures PREDICT members are aware of new members, their interests and areas of expertise and where they are located.  This month we introduce Kamal Singh from the University of Southern Queensland.

“I have been nursing for the last 22 years. My nursing background extensively involves military nursing, emergency care nursing, community health, indigenous health and primary health care nursing. My other research interests include indigenous health care access, health promotion, teaching, and learning.”

Welcome Kamal!

 

“Getting to know you” – Meet new member Nicole Pattison

Our “getting to know you” segment ensures PREDICT members are aware of new members, their interests and areas of expertise and where they are located.  This month we introduce Nicole Pattison from the Royal Children’s Hospital.

My name is Nicole Pattison and I have currently started maternity leave after having a little boy last week. Prior to this I was working at The Royal Children’s Hospital in Melbourne in the NICU as a Paediatric Registrar and plan to return to the Emergency Department in 2020.

I am currently working on a study investigating the public’s perception of clinical Paediatric Emergency Medicine research and hope to further paediatric research in rural and remote areas in the future.

“Getting to know you” – Meet new member Grace Xu

Our “Getting to Know You” segment ensures PREDICT members are aware of new members, their interests and areas of expertise and where they are located.  This month we introduce Grace Xu from QEII Hospital Metro South Health.

Hui (Grace) Xu is an experienced Nurse Practitioner in QEII Hospital ED (Queensland, Brisbane), PhD Candidate at the University of Queensland, Nurse Researcher with the Menzies Health Institute Queensland, and Adjunct Lecturer at Griffith University. Her research interests include staff wellness promotion, paediatric research, vascular access devices and infection prevention. Her passion in promoting staff wellness drives her interest in becoming a key driver and stakeholder of the Staff Wellness Committee in her emergency department.

“Getting to know you” – Meet Lisa Properjohn

Our “Getting to Know You” segment ensures PREDICT members are aware of new members, their interests and areas of expertise and where they are located.  This month we introduce Lisa Properjohn from Perth Children’s Hospital.

“I am a hospital based trained nurse from the Perth Children’s Hospital (formerly Princess Margaret Hospital) where I have worked for the past 35 years.  I have been working in the PCH Emergency Research team for over a year now under the amazing guidance of Sharon O’Brien and Meredith Borland.

I am currently involved with the Paris II study, a Toddler Fracture Cam Boot versus Above Knee Plaster Randomised Control Trial being conducted by PCH ED, the PEA Study in conjunction with the Telethon Kids Institute which is looking to develop a dynamic Antibiogram to guide empiric treatment of UTI’S in children and the PERN Pneumonia Study.

I was lucky enough to meet some of the other awesome PREDICT members in Auckland this year when I attended the BIPED Training for the upcoming BIPED study which we hope to commence this year and I look forward to attending the PREDICT members meeting being held in Perth in October.

 

Project Snapshot – PARIS II

Acute Hypoxemic Respiratory Failure aged 1-4 years

(Paediatric Acute Respiratory Intervention Studies)

Recruitment stats:

Study commenced December 15th 2017

  • >16,872 screened for PARIS II eligibility
  • 2242 eligible
  • 1136 randomised
  • 1070 enrolled (randomised and consented – included for analysis on completion of study)
  • 106 (15%) declined prospective consent
  • 66 (6%) declined delayed consent or unable to obtain

Sites currently recruiting:

  • QCH, Brisbane – 400 recruited (commenced December 2017)
  • RCH, Melbourne – 130 recruited (commenced December 2017)
  • GCUH, Qld – 161 recruited (commenced January 2018)
  • KidzFirst, Middlemore, NZ – 88 recruited (commenced February 2018)
  • JHCH, Newcastle, NSW – 16 recruited (commenced August 2018)
  • Caboolture Hospital, Qld – 10 recruited (commenced August 2018)
  • Ipswich Hospital, Qld – 50 recruited (commenced September 2018)
  • Redcliffe Hospital, Qld – 25 recruited (commenced October 2018)
  • PCH, WA – 78 recruited (commenced November 2018)
  • Starship Children’s Hospital, New Zealand – 48 recruited (commenced December 2018)
  • Monash Health – 10 recruited (commenced December 2018)
  • The Prince Charles Hospital, Qld – 30 recruited (commenced January 2019)
  • Townsville – 8 recruited (commenced January 2019)
  • Waikato Hospital, New Zealand – 16 recruited (commenced July 2019)

No significant issues with processes, eCRF, or site recruitment.

News:

All 14 participating centres are up and recruiting now.  Winter took a while to kick in but eventually did and it has been busy for all centres.  We thank the huge efforts that have been put in place by both the research teams at each centre and the clinical staff recruiting to the study.

We are on track for finishing early!!

 

MRFF Million Minds Projects.

As mentioned in the previous PREDICT newsletter, we have been successful in obtaining funding to conduct a series of projects addressing child and adolescent ED mental health presentations.

We are hoping to better understand, and to improve, care for this vulnerable group of patients.

Our initial projects involve determining
– What are research priorities for patients, families, carers, and healthcare providers?
– What outcome measures are most important?
– What factors influence the care which is delivered?
– What care do we currently provide?

Recently, we have sent out an “Expression of Interest” for the initial three projects, which are outlined further below.

We will be presenting detailed plans for these (and additional projects around the management of acute behavioural disturbance and safety planning for suicidal ideation/self-harm) at the PREDICT member’s meeting in October.

We are hoping that this work will be truly representative of the experience across Australia and New Zealand. Therefore, we are planning to involve up to 30 sites, and are particularly interested to hear from rural, regional, and non-tertiary metropolitan EDs, as well as the larger tertiary EDs.

Funding will be made available to support project set up and data collection.

If you are interested in participating, or have any questions, please contact simon.craig@monash.edu.

Project 1: Delphi Survey
Priorities for research, outcome measures, and discharge communication
Specific aims:
(1) To identify consensus research priorities in ED mental health presentations by children and young people
(2) To identify core outcome measures which should be reported in future studies in specific planned subgroups (suicidality/self-harm; behavioural disturbance; drug and alcohol presentations; eating disorders; and neurodevelopmental disorders such as autism spectrum disorder)
(3) To identify priorities for communication at the point of ED discharge.
Research Design:
An online three-round Delphi process for prioritisation will be conducted with health professionals and health consumers recruited from a range of tertiary paediatric hospitals, metropolitan and rural hospitals across Australia / NZ.

Project 2: Interviews with staff
Factors influencing care and information needs
Specific aims:
(1) To assess information and training needs facing ED clinicians in caring for children and adolescents with acute mental health problems
(2) To understand the factors influencing ED mental health care (e.g. individual beliefs, organisational culture, resources).
Research design:
Qualitative semi-structured interviews. We will conduct qualitative interviews with up to 5 health care providers at participating hospitals.

Project 3: Epidemiology.
Multicentre retrospective study
Specific aims:
(1) To understand the epidemiology of children and young people presenting to the ED with mental health concerns, including their risk profile
(2) To understand in detail the mental health issues of key subgroups (autism and other neurodevelopmental issues, suicidality, drug & alcohol, Indigenous, out-of-home care)
Research design:
Structured retrospective chart review (30 hospitals including tertiary, metropolitan and regional, n=6000, up to 200 mental health ED presentations at each site from 2019). Data will be collected regarding mode of presentation, ED and hospital diagnosis, ED and hospital management, including use of restrictive practices (physical or chemical restraint), healthcare costs, documented risk profiles, co-morbid mental and physical health conditions, and protective factors.

New PREDICT publication

Congratulations to the authors of the following PREDICT publications:

Hopper SM, McKenna S, Williams A, Phillips N, Babl FE, Paediatric Research in Emergency Departments International Collaborative (PREDICT). Clinical clearance and imaging for possible cervical spine injury in children in the emergency department: A retrospective cohort study. Emerg Med Australas. 2019 Jul 17. doi: 10.1111/1742-6723.13351. [Epub ahead of print] [link].

O’Brien S, Craig S, Babl FE, Borland ML, Oakley E, Dalziel SR; Paediatric Research in Emergency Departments International Collaborative (PREDICT) Network, Australasia. Rational use of high-flow therapy in infants with bronchiolitis. What do the latest trials tell us?’ A Paediatric Research in Emergency Departments International Collaborative perspective. 
J Paediatr Child Health. 2019 Jul;55(7):746-752. doi: 10.1111/jpc.14496. [link]

Long E, Babl FE, Oakley E, Hopper S, Sheridan B, Duke T; Paediatric Research in Emergency Departments International Collaborative (PREDICT). Does fluid bolus therapy increase blood pressure in children with sepsis?  Emerg Med Australas. 2019 Jun 25. doi: 10.1111/1742-6723.13336. [Epub ahead of print] [link].

Singh S, Cheek JA, Babl FE, Hoch JS. Review article: A primer for clinical researchers in the emergency department: Part X. Understanding economic evaluation alongside emergency medicine research. Emerg Med Australas. 2019 Jun 24. doi: 10.1111/1742-6723.13320. [Epub ahead of print] Review. [link].

Jamal A, Finkelstein Y, Kuppermann N, Freedman SB, Florin TA, Babl FE, Dalziel SR, Zemek R, Plint AC, Steele DW, Schnadower D, Johnson DW, Stephens D, Kharbanda A, Roland D, Lyttle MD, Macias CG, Fernandes RM, Benito J, Schuh S; Pediatric Emergency Research Networks. Pharmacotherapy in bronchiolitis at discharge from emergency departments within the Pediatric Emergency Research Networks: a retrospective analysis. Lancet Child Adolesc Health. 2019 Aug;3(8):539-547. doi: 10.1016/S2352-4642(19)30193-2. Epub 2019 Jun 7. [link].