Author: Marian Chandler

As well as the list of original “Foundation” PREDICT sites on the “About Us” page on the PREDICT website, we have now added a list of the recent  “non-foundation sites.”  This may be helpful to look at when considering sites for future research projects.

Congratulations to the authors of the following PREDICT publications, which are now available:

Babl FE, Lyttle MD, Bressan S, Borland ML, Phillips N, Kochar A, Dalton S, Cheek JA, Gilhotra Y, Furyk J, Neutze J, Donath S, Hearps S, Arpone M, Crowe L, Dalziel SR, Barker R, Oakley E. Penetrating head injuries in children presenting to the emergency department in Australia and New Zealand: A PREDICT prospective study. J Paediatr Child Health. 2018 Mar 26. doi: 10.1111/jpc.13903. [Epub ahead of print] PMID: 29579354 [link].

Oakley E, Brys T, Borland M, Neutze J, Phillips N, Krieser D2, Dalziel SR, Davidson A, Donath S, Jachno K, South M, Williams A, Babl FE; Paediatric Research in Emergency Departments International Collaborative (PREDICT). Medication use in infants admitted with bronchiolitis. Emerg Med Australas. 2018 Mar 23. doi: 10.1111/1742-6723.12968. [Epub ahead of print] [link].

Craig S, Graudins A, Dalziel SR, Powell CV, Babl FE. Review article: A primer for clinical researchers in the emergency department: Part 6. Measuring what matters: Core outcome sets in emergency medicine research. Emerg Med Australas. 2018 Apr 2. doi: 10.1111/1742-6723.12970. [Epub ahead of print] [link].

Pfeiffer H, Crowe L, Kemp AM, Cowley LE, Smith AS, Babl FE; Paediatric Research in Emergency Departments International Collaborative (PREDICT). Clinical prediction rules for abusive head trauma: a systematic review. Arch Dis Child. 2018 Apr 5. pii: archdischild-2017-313748. doi: 10.1136/archdischild-2017-313748. [Epub ahead of print] [link]

Borland M. L., Dalziel S. R., Phillips N., Dalton S., Lyttle M. D., Bressan S., Oakley E., Hearps S. J. C., Kochar A., Furyk J., Cheek J. A., Neutze J., and Babl F. E., ‘Vomiting with Head Trauma and Risk of Traumatic Brain Injury’, Pediatrics, (2018) 141 (4). [link]

 

 

 

As well as the list of original “Foundation” PREDICT sites on the “About Us” page on the PREDICT website, we have now added a list of the recent  “non-foundation sites“.  This may be helpful to look at when considering sites for future research projects.

Just a reminder that to attend the annual PREDICT members meeting this year in Hobart, participants must be PREDICT members.

If you are not a member and wish to become one, please email Marian (marian.chandler@mcri.edu.au) or Cate (catherine.wilson@mcri.edu.au) for a link to the membership application form.

KIDS THRIVE – trans-nasal Humidified Rapid-Insufflation Ventilatory Exchange In Children Requiring Emergent High Intubation

Investigating the effect of THRIVE as a method for prolonging apnoeic oxygenation during the emergency intubation of children to reduce the proportion adverse events (specifically, oxygen desaturation) and increase the proportion of first attempt success for endotracheal intubation.

Recruitment stats:

• 371 screened for KIDS THRIVE eligibility, (37 ED & 332 PICU)
• 146 enrolled (22 ED & 123 PICU)
• 59 missed patients
• Video collected on 135 patients

Sites currently recruiting:

• RCH, Melbourne – 40 recruited
• LCCH, Brisbane – 96 recruited
• GCUH, Gold Coast – 8 recruited
• Starship, New Zealand- 2 recruited

Sites soon to commence:

• Townsville Emergency Department & Paediatric Intensive Care (May 2018)

News:

This week marks the 145th patient recruited to the KIDS THRIVE Trial which is a tribute to everyone’s hard work and dedication to this project. The KIDS THRIVE team have also submitted NHMRC application and have been successful in completing the first phase of the Thrasher Research Fund process for further funding of this important work.

We now have a KIDS THRIVE web page hosted on the Children’s Health Queensland site. It gives both parents and sites some general information about the study and to show case the amazing work we are doing. You can also keep up to date with the KIDS THRIVE project on Twitter @KIDSTHRIVE.

The KIDS THRIVE study team would like to take this opportunity to thank all sites for their enormous effort over the last few months.

Chief Investigators A/Prof Andreas Schibler, Dr Shane George, Dr Susan Humphreys, Dr Ben Gelbart and Study Co-ordinator Tara Williams

….. Next month we feature KT Bronchiolitis Project: Sharon O’Brien/Libby Haskell.

As well as the list of original “Foundation” PREDICT sites on the “About Us” page on the PREDICT website, we have now added a list of the recent  “non-foundation sites“.  This may be helpful to look at when considering sites for future research projects.

To ensure PREDICT members are aware of new members and where they are located, we will be featuring our new segment “Getting to know you” in our monthly newsletter.  This month we introduce Nicole Ghedina, from St John of God Midland Hospital.

“I am a FACEM at St John of God Midland ED, a mixed ED in the North Eastern suburbs of Perth, with a census of about 72,000 presentations per year of which about 20% are paediatric. We have an emerging research program and have joined with a number of multi-centre projects such as the ANZEDAR, prehospital CPAP, and ASP. We also run an active clinical audit program with a strong paediatric focus. We are keen to be involved with multi-centre ED based research and research translation projects.”

To ensure PREDICT members are aware of new members and where they are located, we will be featuring our new segment “Getting to know you” in our monthly newsletter.  This month we introduce Melissa Spooner a registered nurse from Hawkes Bay Hospital, New Zealand.

“I work at Hawke’s Bay Hospital in the Clinical Trials Research Unit which covers a lot of different therapeutic areas – mainly adult medicine.

I have one day a week dedicated to paediatrics which is my main interest, so of course our team is interested in every aspect of paediatric research and hoping to increase this.  We are always on the lookout for more trials – mainly medical.

I have worked within paediatrics for approximately 18 years as a nurse and was introduced to the research side in 2005 and thoroughly enjoyed it, so here I still am.

At the moment we have trials looking at Bronchiolitis, Oximetry in premature babies and Dextrose gel in high risk new born babies on the go.

I am very happy to have joined the PREDICT team and look forward to what the future entails.”

 

Ready to go!:

Ethics approval has been granted and the RedCAP database has been constructed and tested.  You should all have received email instructions on how to get going.

The main steps are:

• Compile a list of who will be doing the data entry
• Send the list to Simon Craig who will give access to the training environment.
• Extract a list of medical records, and follow the emailed instructions to set up REDCap
• Once you are happy with the data entry process, get access to the real database and make a start!

Please let Simon know if there are any queries.

COMING SOON – International (PREDICT-led) Asthma Projects:

An international working group, with representatives from all PERN research networks has been formed to look at outcome measures in clinical trials of acute severe paediatric asthma. A number of projects are being planned, and will be circulated through PREDICT as they develop.

The first series of projects will include

• collation of clinical practice guidelines (lead – Simon Craig)
• interviews with clinicians (lead – Charmaine Gray)
• interviews with patients (lead – Simon Craig)

Please contact Simon (simon.craig@monash.edu) with any queries.

….. Next month we feature Kids THRIVE  Shane George.

The annual EMF Grants Award Ceremony was held on 13th March 2018 where 2017-18 grant recipients were recognised. Two PREDICT projects received awards – Asthma study “How are we treating severe childhood asthma in Australasia?” (Dr Ben Lawton) and APHIRST- Gap (Dr Natalie Phillips, accepted Leanne Diggelman from Lady Cilento Children’s Hospital).