The PREDICT members meeting has been moved to 15th November 2023. An amended calendar invite has been forwarded to all members. Please accept the invite to ensure you have the correct date in your calendar. The event will be held in Melbourne at the Murdoch Children’s Research Institute.
Author: Marian Chandler
Present your “New Research Idea” at PREDICT Members meeting (15/11/23)
We have scheduled up to three “New research idea” presentations at the PREDICT members meeting being held face to face and via ZOOM on Wednesday 15th of November 2023.
Do you have a proposal you would like to develop and present for feedback?
If so, please email the PREDICT research co-ordinator Catherine.wilson@mcri.edu.au, a 1 – 2 page proposal by Friday 13th October 2023.
The 3 researchers selected to present their idea will receive mentoring from one of the PREDICT Executive with relevant expertise.
Presenters will be given 5 minutes to present the idea with an extra 10 minutes for discussion and questions. Presentations will be confirmed by 20th October 2023 and presentation times given later on.
SAVE THE DATE – PREDICT members meeting 15th November 2023
The PREDICT members meeting has been moved to 15th November 2023. An amended calendar invite has been forwarded to all members. Please accept the invite to ensure you have the correct date in your calendar. The event will be held in Melbourne at the Murdoch Children’s Research Institute.
Getting to know you – meet Helen Goldsmith
Our “Getting to Know You” segment ensures PREDICT members are aware of new members, their interests and areas of expertise and where they are located.
This month we introduce Helen Goldsmith from the Sydney Children’s Hospital Network.
“I have been a registered nurse for over 25 years, and I have more than 20 years of experience conducting clinical trials, research projects and quality improvement initiatives with hospital clinicians, patients, and carers in a variety of disciplines and settings. I have always had an interest in emergency/trauma research; and I completed my PhD in 2018 investigating “The Incidence, Impact and Experience of Pain in Recently Discharged Adult Trauma Patients”. I have only recently commenced working in paediatrics. I am currently the Research Development Manager with the Sydney Children’s Hospitals Network, and my role involves promoting, encouraging, embedding, and supporting clinical research.”
Welcome to PREDICT Helen!
Getting to know you – meet Samantha Luck
Our “Getting to Know You” segment ensures PREDICT members are aware of new members, their interests and areas of expertise and where they are located.
This month we introduce Samantha Luck from Toowoomba Hospital and QCH.
“My name is Samantha Luck, and I work part-time in Toowoomba, a regional mixed Emergency Department, as an emergency staff specialist and part-time as a paediatric emergency medicine fellow in Queensland Children’s Hospital to complete post-fellowship PEM training. I am passionate about ensuring that regional and mixed Emergency Departments provide the highest possible standard of care, and so am looking forward to engaging with this network.”
Welcome to PREDICT Samantha!
Project Snapshot – Bronchiolitis sustainability study
Sustaining improvements in the management of infants with bronchiolitis – a PREDICT study
Co-ordinating PI:
Emma Tavender, Sandy Middleton, Stuart Dalziel.
Study Co-ordinator
Emma Tavender, PhD student: Victoria Ramsden.
Project aim/s:
The aim of this study is to:
i) determine if the use of targeted interventions from the PREDICT Bronchiolitis KT Study have been effective at sustaining improvements in evidence-based practices in Australasian paediatric acute care settings one and two years after completion of the trial at intervention group hospitals (n=13);
ii) determine if there are any improvements in control group hospitals (n=13);
iii) understand the factors which influenced the sustainability of improvements in intervention group hospitals and;
iv) explore factors which may have contributed to improvements at control group hospitals.
Study design:
A mixed-methods study design: retrospective medical record audit (approximately 150 infants per site for the years 2018 and 2019) and qualitative semi-structured individual or group interviews (3-5 individuals per site).
Primary outcome:
Outcomes: medical record audit
The proportion of infants presenting with bronchiolitis to intervention and control group hospitals, who received care that adhered with five inappropriate therapies (chest X-ray, salbutamol, glucocorticoids, antibiotics, and adrenaline) one year (2018) and two years (2019) following delivery of an intervention designed to promote evidence-based practice adherence (composite of all five practices).
Outcomes: Qualitative interviews:
Factors that contributed to sustainability of improvements of evidence-based practice adherence at intervention group hospitals four years post-implementation; Factors that contributed to improvements/deterioration of evidence-based practice adherence at control group hospitals four years post-implementation; Fidelity and adaptation to the PREDICT Bronchiolitis KT Study implementation strategy at intervention and control group hospitals four years following intervention delivery (2018, 2019, 2020, 2021) (Control group hospitals received the intervention materials post trial completion).
Current status:
16 Australian and 6 New Zealand sites recruited. All sites have completed governance and commenced the study. Medical Record Audit data collection has been completed at 18 sites. Remaining four sites should be completed soon. Qualitative interviews are now completed at the 9 Australian and 2 New Zealand intervention hospitals.
Publications:
Ramsden, V., Babl, F.E., Dalziel, S.R. et al. Sustainability of evidence-based practices in the management of infants with bronchiolitis in hospital settings – a PREDICT study protocol. BMC Health Serv Res 22, 1099 (2011).
RA study days – Melbourne 24 & 25 July
Planning is well under way for the two day face-to-face Research Nurse/Assistant education session to be held at the RCH Melbourne on 24th and 25th July 2023.
Participants have been finalised and flights and accommodation confirmed.
Studies to be covered are:
- Mental Health Prospective Observational Study
- Asthma Prospective Study
- Febrile Convulsions (FEBCON)
- CHOICE UTI
- SPASMs
NB. The SONIC, PROMPT Bolus/Sentinel and PEACHY O & M Co-ordinators will also be present at a designated time during the two days to answer any questions you may have about these studies that are now well underway.
We will cover all study related topics including governance applications, study oversight, in depth study specific education, databases, legal contracts, GCP and recruitment.
Participants will receive an email in the next few weeks confirming arrangements such as access to MCRI, Larwill check-in process and general housekeeping.
New PREDICT publications
Congratulations to the following PREDICT authors:
George S, Gibbons K, Williams T, Humphreys S, Gelbart B, Le Marsney R, Craig S, Tingay D, Chavan A, Schibler A; Kids THRIVE Investigators; Paediatric Research in Emergency Departments International Collaborative (PREDICT); Australia, New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG). Transnasal Humidified Rapid Insufflation Ventilatory Exchange in children requiring emergent intubation (Kids THRIVE): a statistical analysis plan for a randomised controlled trial. Trials. 2023 May 31;24(1):369. doi: 10.1186/s13063-023-07330-z. PMID: 37259146; PMCID: PMC10230452.
SAVE THE DATE – RA study days – Melbourne 24 & 25 July
Planning is under way for a two day face-to-face Research Nurse/Assistant education session to be held at the RCH Melbourne on 24th and 25th July 2023.
Please advise your intention to attend as soon as possible on the form emailed to you. Flights can be advised later.
Studies to be covered are:
- Mental Health Prospective Observational Study
- Asthma Prospective Study
- Febrile Convulsions (FEBCON)
- CHOICE UTI
- SPASMs
NB. The SONIC, PROMPT Bolus/Sentinel and PEACHY O & M Co-ordinators will also be present at a designated time during the two days to answer any questions you may have about these studies that are now well underway.
We have run similar education days in the past and they have been extremely successful. We highly recommend that you attend if working on these studies. We will cover all study related topics including governance applications, study oversight, in depth study specific education, databases, legal contracts, GCP and recruitment.
Please save these dates in your diaries. Formal invitations are being sent to site co-ordinators soon. This will include detailed information on funding and the process for booking flights and accommodation.
New PREDICT publications
Congratulations to the following PREDICT authors:
Ibrahim L, Wilson C, Tham D, Corden M, Jani S, Zhang M, Kochar A, Tan KF, George S, Phillips NT, Buntine P, Robins-Browne K, Chong V, Georgeson T, Lithgow A, Davidson S, O’Brien S, Tran V, Babl FE. The characteristics of SARS-CoV-2-positive children in Australian hospitals: a PREDICT network study. Med J Aust. 2023 Apr 22. doi: 10.5694/mja2.51934. Epub ahead of print. PMID: 37087105.
Solan T, Cudini D, Humar M, Forsyth N, Meadley B, St Clair T, Hodge D, Smith K, Babl FE, Long E. Characteristics of paediatric pre-hospital intubation by Intensive Care Paramedics. Emerg Med Australas. 2023 Apr 5. doi: 10.1111/1742-6723.14207. Epub ahead of print. PMID: 37019689.
Babl FE, Eapen N, Herd D, Borland ML, Kochar A, Zhang M, Oakley E, Hopper SM, Berkowitz RG, Wilson CL, Williams A, Mackay MT, Lee KJ, Hearps S; PREDICT (Paediatric Research in Emergency Departments International Collaborative) research network. Agreement of Clinician-Administered and Modified Parent-Administered House-Brackmann Scales in Children with Bell’s Palsy. OTO Open. 2023 Mar 24;7(1):e44. doi: 10.1002/oto2.44. PMID: 36998545; PMCID: PMC10046699.
Williams A, Eapen N, Kochar A, Lawton B, Hort J, West A, George S, Berkowitz R, Lee KJ, Dalziel SR, Hearps S, Babl FE; PREDICT (Paediatric Research in Emergency Departments International Collaborative) research network. Agreement Between House-Brackmann and Sunnybrook Facial Nerve Grading Systems in Bell’s Palsy in Children: Secondary Analysis of a Randomized, Placebo-Controlled Multicenter Trial. J Child Neurol. 2023 Feb;38(1-2):44-51. doi: 10.1177/08830738221144082. Epub 2023 Feb 5. PMID: 36740927.
Xiong X, Huang L, Herd D, Borland M, Davidson A, Hearps S, Mackay MT, Lee KJ, Dalziel SR, Dalziel K, Cheek JA, Babl FE. Cost-effectiveness of Prednisolone to Treat Bell Palsy in Children: An Economic Evaluation Alongside a Randomized Controlled Trial. Neurology. 2023 Apr 18:10.1212/WNL.0000000000207284. doi: 10.1212/WNL.0000000000207284. Epub ahead of print. PMID: 37072220.